化工系
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陈杜刚,博士,副教授/硕士生导师

地址:湖北省武汉市东湖新技术开发区光谷一路206

邮编:430205

Emaildg.chen@163.com

教育背景

2007−2012  武汉大学,化学与分子科学学院,博士

2003−2007  武汉大学,化学与分子科学学院,学士

工作履历

2018年至今       8159金沙登录,8159金沙登录,副教授

2019−2020    Georgia Institute of Technology,访问学者

2016−2018    8159金沙登录,8159金沙登录,讲师

研究领域

1)智能分子影像材料及其生物医学应用化学传感;光学治疗;聚集诱导发光

2)芯片产业相关高端磷/硅化学品:磷系阻燃剂;硅微粉;超疏水硅树脂;气凝胶

招收化学工艺、物理化学、化学工程、制药化学、材料与化工等方向的研究生。

学术成果

近年来部分SCI论文:

 (1) Dai, J.; Xue, H.; Chen, D.; Lou, X.; Xia, F.; Wang, S., Aggregation-induced emission luminogens for assisted cancer surgery. Coord. Chem. Rev. 2022, 464, 214552.IF>20

 (2) Yin, S.; Chen, Z.; Chen, D.; Yan, D., Strategies targeting PD-L1 expression and associated opportunities for cancer combination therapy. Theranostics 2023, 13, 1520-1544. ( IF>10)

 (3) Liang, W.; Nie, G.; Che, J.; Zhang, Z.; Chen, D.; Wu, W., A ratiometric hypochlorite-specific nanoprobe constructed by rationally designed AIE luminogen for fluorescence imaging of alcoholic liver disease. Sens. Actuators B. Chem. 2023, 384, 133648.

 (4) Li, W.; Nie, G.; Yang, A.; Qu, J.; Zhong, C.; Chen, D., Exploring the microscopic changes of lipid droplets and mitochondria in alcoholic liver disease via fluorescent probes with high polarity specificity. Talanta 2023, 265, 124819.

 (5) Nie, G.; Che, J.; Feng, Y.; Liang, W.; Chen, D.; Wang, H., AIE fluorescent probes for monitoring cell membrane fluidity/lipid droplet change during alcoholic liver disease. Dyes Pigm. 2023, 219, 111535.

 (6) Feng, Y.; Nie, G.; Liang, W.; Li, W.; Zhang, Y.; Wang, K.; Chen, D., Real-time imaging of acute alcoholic liver injury in vivo via a robust viscosity probe with aggregation-induced emission nature. Sens. Actuators B. Chem. 2022, 355, 131285.

 (7) Chen, D.; Feng, Y., Recent Progress of Glutathione (GSH) Specific Fluorescent Probes: Molecular Design, Photophysical Property, Recognition Mechanism and Bioimaging. Crit. Rev. Anal. Chem. 2022, 52, 649-666.

 (8) Chen, D.; Long, Z.; Zhong, C.; Chen, L.; Dang, Y.; Hu, J.-J.; Lou, X.; Xia, F., Highly Efficient Near-Infrared Photosensitizers with Aggregation-Induced Emission Characteristics: Rational Molecular Design and Photodynamic Cancer Cell Ablation. ACS Appl. Bio Mater. 2021, 4, 5231-5239.

 (9) Chen, L.; Feng, Y.; Dang, Y.; Zhong, C.; Chen, D., A deep-red emission fluorescent probe with long wavelength absorption for viscosity detection and live cell imaging. Anal. Bioanal. Chem. 2020, 412, 7819-7826.

(10) 王孔琛,冯杨振,陈杜刚,粘度刺激响应的荧光探针研究进展,分析科学学报202238779-787.

授权发明专利:

1)一种发射近红外光的荧光染料及其制备方法,ZL201910519410.X

2)一种溶酶体靶向荧光探针及其制备方法,ZL201710470889.3

3)一种双通道铜离子检测试纸及其制备方法,ZL201710952218.0

4)一种远红光溶酶体荧光探针及其制备方法和应用,ZL202011175030.8

5)具有近红外发射、高单线态氧产率的聚集诱导发光型光敏剂及其制备方法、应用,ZL202110338852.1

6)具有聚集诱导发光特性的水溶性荧光探针及其制备方法、应用,ZL202111009124.2

7)一种靶向线粒体的AIE型次氯酸荧光探针及其制备方法、应用,ZL202210453336.8

科研项目                                                                        

国家自然科学基金青年项目,主持

湖北省教育厅科学研究计划重点项目,主持

多项企业委托项目

其它荣誉                                                                         

指导研究生多人次获“优秀硕士学位论文”;指导本科生多人次以第一作者发表科研论文;指导本科生/研究生多人次获“互联网+”大学生创新创业大赛校赛奖项。

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